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BRCA2 Antikörper

BRCA2 Reaktivität: Human WB Wirt: Maus Monoclonal F2H5 unconjugated
Produktnummer ABIN7090792
  • Target Alle BRCA2 Antikörper anzeigen
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Reaktivität
    • 43
    • 23
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 6
    Maus
    Klonalität
    • 42
    • 7
    Monoklonal
    Konjugat
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser BRCA2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 15
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Human
    Immunogen
    Recombinant human BRCA2_HUMAN.
    Klon
    F2H5
    Top Product
    Discover our top product BRCA2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Andere Bezeichnung
    BRCA2 (BRCA2 Produkte)
    Synonyme
    BRCC2 antikoerper, BROVCA2 antikoerper, FACD antikoerper, FAD antikoerper, FAD1 antikoerper, FANCB antikoerper, FANCD antikoerper, FANCD1 antikoerper, GLM3 antikoerper, PNCA2 antikoerper, 30169 antikoerper, BcDNA:SD25109 antikoerper, CG13583 antikoerper, CG13584 antikoerper, CG30169 antikoerper, Dmel\\CG30169 antikoerper, brca2 antikoerper, dmbrca2 antikoerper, fancd1 antikoerper, BRCA2 antikoerper, brcc2 antikoerper, brovca2 antikoerper, facd antikoerper, fad antikoerper, fad1 antikoerper, fancb antikoerper, AI256696 antikoerper, AW045498 antikoerper, Fancd1 antikoerper, RAB163 antikoerper, BRCA2, DNA repair associated antikoerper, Breast cancer 2, early onset homolog antikoerper, breast cancer 2, early onset antikoerper, BRCA2 antikoerper, Brca2 antikoerper, brca2 antikoerper, LOC584780 antikoerper
    Hintergrund

    Synonyms: BRCA 2, BRCA1/BRCA2 containing complex subunit 2, BRCC 2, BRCC2, Breast and ovarian cancer susceptibility gene early onset, Breast cancer 2 early onset, Breast Cancer 2 tumor suppressor, Breast cancer susceptibility protein BRCA2, Breast cancer type 2 susceptibility protein, FACD, FAD 1, FAD, FAD1, FANCB, FANCD 1, FANCD, FANCD1, Fanconi anemia complementation group D1, Fanconi anemia group D1 protein, OTTHUMP00000018803, OTTHUMP00000042401, BRCA2_HUMAN.

    Background: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. In concert with NPM1, regulates centrosome duplication.

    Gen-ID
    675
    UniProt
    P51587
    Pathways
    DNA Reparatur, M Phase, Maintenance of Protein Location
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