Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

BRCA2 Antikörper

BRCA2 Reaktivität: Human WB Wirt: Maus Monoclonal F2H5 unconjugated
Produktnummer ABIN7090792
  • Target Alle BRCA2 Antikörper anzeigen
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Reaktivität
    • 35
    • 16
    • 13
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 6
    Maus
    Klonalität
    • 34
    • 7
    Monoklonal
    Konjugat
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BRCA2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 15
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Human
    Immunogen
    Recombinant human BRCA2_HUMAN.
    Klon
    F2H5
    Top Product
    Discover our top product BRCA2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Andere Bezeichnung
    BRCA2 (BRCA2 Produkte)
    Hintergrund

    Synonyms: BRCA 2, BRCA1/BRCA2 containing complex subunit 2, BRCC 2, BRCC2, Breast and ovarian cancer susceptibility gene early onset, Breast cancer 2 early onset, Breast Cancer 2 tumor suppressor, Breast cancer susceptibility protein BRCA2, Breast cancer type 2 susceptibility protein, FACD, FAD 1, FAD, FAD1, FANCB, FANCD 1, FANCD, FANCD1, Fanconi anemia complementation group D1, Fanconi anemia group D1 protein, OTTHUMP00000018803, OTTHUMP00000042401, BRCA2_HUMAN.

    Background: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. In concert with NPM1, regulates centrosome duplication.

    Gen-ID
    675
    UniProt
    P51587
    Pathways
    DNA Reparatur, M Phase, Maintenance of Protein Location
Sie sind hier:
Kundenservice