DDX4 Antikörper (C-Term)

Produktnummer ABIN7091031

Produktdetails anti-DDX4 Antikörper

Target: DDX4 (DEAD Box Protein 4 (DDX4))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDX4 C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DDX4

Target: DDX4 (DEAD Box Protein 4 (DDX4))

Andere Bezeichnung: DDX4 (DDX4 Produkte)

Synonyme: VASA antikoerper, AV206478 antikoerper, Mvh antikoerper, RVLG antikoerper, vasa antikoerper, vlg1 antikoerper, DEAD-box helicase 4 antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 antikoerper, DEAD-box helicase 4 L homeolog antikoerper, DDX4 antikoerper, Ddx4 antikoerper, ddx4.L antikoerper

Hintergrund:

Synonyms: DDX 4, DEAD (Asp Glu Ala Asp) box polypeptide 4, Dead box protein 4, Dead-box protein 4, MGC111074, MVH, Probable ATP dependent RNA helicase DDX4, VASA, VASA homolog, DDX4_HUMAN.

Background: ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity). Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity).

Gen-ID: 54514

UniProt: Q9NQI0