IL23R Antikörper (AA 231-330) (Biotin)
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- Target Alle IL23R Antikörper anzeigen
- IL23R (Interleukin 23 Receptor (IL23R))
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Bindungsspezifität
- AA 231-330
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL23R Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Homologie
- Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IL-23R
- Isotyp
- IgG
- Top Product
- Discover our top product IL23R Primärantikörper
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- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- IL23R (Interleukin 23 Receptor (IL23R))
- Andere Bezeichnung
- IL-23R (IL23R Produkte)
- Synonyme
- IL-23R antikoerper, IL23R antikoerper, il-23r antikoerper, interleukin 23 receptor antikoerper, IL23R antikoerper, il23r antikoerper, Il23r antikoerper
- Hintergrund
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Synonyms: IL23 Receptor, IL-23R, IL23R, interleukin 23 receptor, IL 23R, IL-23 receptor, IL23R_HUMAN, Interleukin-23 receptor.
Background: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.
- Gen-ID
- 149233
- UniProt
- Q5VWK5
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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