RHOBTB2 Antikörper (AA 631-727)

Produktnummer ABIN706241

Produktdetails anti-RHOBTB2 Antikörper

Target: RHOBTB2 (rho-Related BTB Domain Containing 2 (RHOBTB2))

Bindungsspezifität: AA 631-727

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOBTB2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DBC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RHOBTB2

Target: RHOBTB2 (rho-Related BTB Domain Containing 2 (RHOBTB2))

Andere Bezeichnung: DBC2 (RHOBTB2 Produkte)

Synonyme: DBC2 antikoerper, Dbc2 antikoerper, E130206H14Rik antikoerper, mKIAA0717 antikoerper, Rho related BTB domain containing 2 antikoerper, Rho-related BTB domain containing 2 antikoerper, RHOBTB2 antikoerper, Rhobtb2 antikoerper

Hintergrund:

Synonyms: DBC2, Rho-related BTB domain-containing protein 2, Deleted in breast cancer 2 gene protein, p83, RHOBTB2, KIAA0717

Background: DBC2 is a member of the recently identified RhoBTB family, which is part of the Rho GTPase family. DBC2 has been implicated as a tumor suppressor in breast and lung cancer. Studies have shown that DBC2 binds to the ubiquitin ligase scaffold Cul3, and that Cul3 regulates DBC2 protein levels by ubiquitinating DBC2 directly, leading to its degradation by the proteasome.

Gen-ID: 23221

UniProt: Q9BYZ6