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PKD2 Antikörper (AA 41-140)

PKD2 Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7091534
  • Target Alle PKD2 Antikörper anzeigen
    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
    Bindungsspezifität
    • 15
    • 13
    • 11
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-140
    Reaktivität
    • 65
    • 54
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 72
    • 3
    • 1
    Kaninchen
    Klonalität
    • 74
    • 3
    Polyklonal
    Konjugat
    • 40
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PKD2 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 41
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Cow,Pig,Horse,Rabbit,Zebrafish
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Polycystin 2
    Isotyp
    IgG
    Top Product
    Discover our top product PKD2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
    Andere Bezeichnung
    Polycystin 2 (PKD2 Produkte)
    Synonyme
    APKD2 antikoerper, PC2 antikoerper, PKD4 antikoerper, Pc-2 antikoerper, TRPP2 antikoerper, C030034P18Rik antikoerper, RGD1559992 antikoerper, pkd2 antikoerper, trpp2 antikoerper, Cup antikoerper, PKD2L1 antikoerper, polycystin 2, transient receptor potential cation channel antikoerper, polycystic kidney disease 2 antikoerper, Polycystin-2 antikoerper, polycystin 2, transient receptor potential cation channel L homeolog antikoerper, PKD2 antikoerper, Pkd2 antikoerper, pkd-2 antikoerper, pkd2.L antikoerper, pkd2 antikoerper
    Hintergrund

    Synonyms: polycystic kidney disease 2, TRPP2, APKD2, C030034P18RIK, MGC138466, MGC138468, PC2, PKD2 (includes EG:5311), PKD4, POLYCISTIN-2, POLYCYSTIN 2, RGD1559992, TRPP2, Polycystic kidney disease 2 protein homolog, PC2.

    Background: Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel.

    Gen-ID
    5311
    UniProt
    Q13563
    Pathways
    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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