R-Spondin 3 Antikörper (AA 22-100)

Produktnummer ABIN7091621

Produktdetails anti-R-Spondin 3 Antikörper

Target: R-Spondin 3 (RSPO3)

Bindungsspezifität: AA 22-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser R-Spondin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Cat,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPO3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu R-Spondin 3

Target: R-Spondin 3 (RSPO3)

Andere Bezeichnung: RSPO3 (RSPO3 Produkte)

Synonyme: pwtsr antikoerper, thsd2 antikoerper, cristin1 antikoerper, CRISTIN1 antikoerper, PWTSR antikoerper, THSD2 antikoerper, RGD1563246 antikoerper, 2810459H04Rik antikoerper, AW742308 antikoerper, Cristin1 antikoerper, Thsd2 antikoerper, R-spondin 3 antikoerper, rspo3 antikoerper, RSPO3 antikoerper, Rspo3 antikoerper

Hintergrund:

Synonyms: CRISTIN1, hPWTSR, hRspo3, Protein with TSP type-1 repeat, PWTSR, R-spondin 3 homolog, R-spondin-3 [Precursor], R-spondin-3, Roof plate specific spondin-3, Roof plate-specific spondin-3, RSPO3_HUMAN, Thrombospondin type I domain containing 2, Thrombospondin type-1 domain-containing protein 2, THSD2.

Background: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

Gen-ID: 84870

UniProt: Q9BXY4