CD33 Antikörper (AA 18-269)
-
- Target Alle CD33 Antikörper anzeigen
- CD33
-
Bindungsspezifität
- AA 18-269
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD33 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), ELISA
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Immunogen
- Recombinant human CD33 (Asp18-His269) (ABIN6961110) produced by using human HEK293 cells
- Klon
- DM77
- Isotyp
- IgG
- Top Product
- Discover our top product CD33 Primärantikörper
-
anti-CD33 (CD33) (AA 101-200) antibody
CD33 Reaktivität: Human, Maus FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 Reaktivität: Human FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, CyTOF Wirt: Maus Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, CyTOF Wirt: Maus Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibody (Biotin)CD33 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal HIM3-4 Biotin
anti-CD33 (CD33) antibody (FITC)CD33 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal WM53 FITC
-
- Applikationshinweise
- ELISA 1/5000-10000,Flow Cyt 1/100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
-
- Target
- CD33
- Andere Bezeichnung
- CD33 (CD33 Produkte)
- Synonyme
- SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper
- Hintergrund
-
Synonyms:CD33,SIGLEC3,gp67
Description:Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked sialic acid-bearing glycans. Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK. These phosphorylations provide docking sites for the recruitment and activation of protein-tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. In turn, these phosphatases regulate downstream pathways through dephosphorylation of signaling molecules. One of the repressive effect of CD33 on monocyte activation requires phosphoinositide 3-kinase/PI3K. - Molekulargewicht
- 39.8kDa
- Gen-ID
- 945
- UniProt
- P20138
-
