CD86 Antikörper (AA 26-247)
-
- Target Alle CD86 Antikörper anzeigen
- CD86
-
Bindungsspezifität
- AA 26-247
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD86 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), ELISA
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Immunogen
- Recombinant human B7-2 (Leu26-Pro247) (ABIN6961107) produced by using human HEK293 cells
- Klon
- DM84
- Isotyp
- IgG
- Top Product
- Discover our top product CD86 Primärantikörper
-
-
- Applikationshinweise
- ELISA 1/5000-10000,Flow Cyt 1/100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
-
- Target
- CD86
- Andere Bezeichnung
- B7-2 (CD86 Produkte)
- Synonyme
- B7-2 antikoerper, B7.2 antikoerper, B70 antikoerper, CD28LG2 antikoerper, LAB72 antikoerper, B7 antikoerper, CLS1 antikoerper, Cd28l2 antikoerper, ETC-1 antikoerper, Ly-58 antikoerper, Ly58 antikoerper, MB7 antikoerper, MB7-2 antikoerper, TS/A-2 antikoerper, CD86 molecule antikoerper, CD86 antigen antikoerper, integrin subunit alpha 2b antikoerper, CD86 antikoerper, Cd86 antikoerper, Itga2b antikoerper
- Hintergrund
-
Synonyms:CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Description:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. - Molekulargewicht
- 37.7kDa
- Gen-ID
- 942
- UniProt
- P42081
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
-