TNFSF14 Antikörper (AA 99-330)

Produktnummer ABIN7092969

Produktdetails anti-TNFSF14 Antikörper

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Bindungsspezifität: AA 99-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TNFSF14 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Aufreinigung: Powder

Immunogen: Recombinant human LIGHT(Glu99-Ala330) (ABIN7092666) produced by using human HEK293 cells

Klon: DM170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1/5000-10000,Flow Cyt 1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu TNFSF14

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Andere Bezeichnung: LIGHT (TNFSF14 Produkte)

Synonyme: TNFSF14 antikoerper, CD258 antikoerper, HVEML antikoerper, LIGHT antikoerper, LTg antikoerper, TR2 antikoerper, HVEM-L antikoerper, Ly113 antikoerper, TNF superfamily member 14 antikoerper, tumor necrosis factor (ligand) superfamily, member 14 antikoerper, TNFSF14 antikoerper, Tnfsf14 antikoerper

Hintergrund: Synonyms:TNFSF14, CD258, HVEML, LIGHT, LTg
Description:The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Molekulargewicht: 26.4KDa

Pathways: Cancer Immune Checkpoints