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HNRNPK Antikörper (AA 201-300)

Name: HNRNPK Antikörper (AA 201-300)
SKU: ABIN706571
Price: 384.62 EUR
Availability: InStock

HNRNPK Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Lane 1:A549 cell lysates probed with Rabbit Anti-hnRNP K Polyclonal Antibody, Unconjugated (ABIN706571) at 1:300 overnight at 4 °C. (HNRNPK Antikörper (AA 201-300))

1 image

Produktnummer ABIN706571

Datenblatt (PDF)

Target Alle HNRNPK Antikörper anzeigen

HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
Bindungsspezifität
14

14

10

7

5

4

2

2

2

2

1

1

1

1

1

1

1

1
AA 201-300
Reaktivität
83

60

55

11

10

10

8

7

7

7

6

5

3

2

2

1

1
Human, Maus, Ratte
Wirt
75

9
Kaninchen
Passende Sekundärantikörper
Klonalität
68

16
Polyklonal
Konjugat
49

4

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser HNRNPK Antikörper ist unkonjugiert
Applikation
62

23

20

13

13

13

12

10

4

3

3

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human hnRNP K

Isotyp

IgG

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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibody
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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 371-420) antibody
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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (C-Term) antibody
HNRNPK Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Andere Bezeichnung

hnRNP K (HNRNPK Produkte)

Synonyme

CSBP antikoerper, HNRPK antikoerper, TUNP antikoerper, Csbp antikoerper, Hnrpk antikoerper, hnrpk antikoerper, MGC75642 antikoerper, wu:fb37h02 antikoerper, wu:fi34c04 antikoerper, zgc:66162 antikoerper, KBBP antikoerper, NOVA antikoerper, heterogeneous nuclear ribonucleoprotein K antikoerper, heterogeneous nuclear ribonucleoprotein K S homeolog antikoerper, heterogeneous nuclear ribonucleoprotein k antikoerper, HNRNPK antikoerper, Hnrnpk antikoerper, hnrnpk.S antikoerper, hnrnpk antikoerper, LOC5565718 antikoerper, CpipJ_CPIJ000130 antikoerper, NGK_p0004 antikoerper

Hintergrund

Synonyms: CSBP, TUNP, HNRPK, Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, HNRNPK
Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.

Gen-ID

3190

UniProt

P61978