Bestrophin 1 Antikörper

Produktnummer ABIN7111981

Produktdetails anti-Bestrophin 1 Antikörper

Target: Bestrophin 1 (BEST1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: bestrophin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Bestrophin 1

Target: Bestrophin 1 (BEST1)

Andere Bezeichnung: Bestrophin-1 (BEST1 Produkte)

Synonyme: CG6264 antikoerper, Dbest antikoerper, Dmel\\CG6264 antikoerper, anon-WO0118547.380 antikoerper, best antikoerper, dBest1 antikoerper, dbest1 antikoerper, dmBest1 antikoerper, BEST1 antikoerper, VMD2 antikoerper, best-1 antikoerper, ARB antikoerper, BEST antikoerper, BMD antikoerper, RP50 antikoerper, TU15B antikoerper, Bmd antikoerper, Vmd2 antikoerper, mBest1 antikoerper, Bestrophin 1 antikoerper, bestrophin 1 antikoerper, Best1 antikoerper, BEST1 antikoerper, best1 antikoerper, Bm1_25500 antikoerper

Hintergrund: Synonyms:BEST Background:This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Molekulargewicht: 70 kDa

Gen-ID: 7439

UniProt: O76090