CNOT3 Antikörper
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- Target Alle CNOT3 Antikörper anzeigen
- CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CNOT3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- CCR4-NOT transcription complex, subunit 3
- Isotyp
- IgG
- Top Product
- Discover our top product CNOT3 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
- Andere Bezeichnung
- CNOT3 (CNOT3 Produkte)
- Hintergrund
- Synonyms:KIAA0691, LENG2, NOT3 Background:Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.
- Molekulargewicht
- 120 kDa
- Gen-ID
- 4849
- UniProt
- O75175
- Pathways
- Stem Cell Maintenance
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