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CNOT3 Antikörper

CNOT3 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7112435
  • Target Alle CNOT3 Antikörper anzeigen
    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
    Reaktivität
    • 33
    • 10
    • 10
    • 10
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 30
    • 3
    Kaninchen
    Klonalität
    • 30
    • 3
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser CNOT3 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 16
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    CCR4-NOT transcription complex, subunit 3
    Isotyp
    IgG
    Top Product
    Discover our top product CNOT3 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
    Andere Bezeichnung
    CNOT3 (CNOT3 Produkte)
    Hintergrund
    Synonyms:KIAA0691, LENG2, NOT3 Background:Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.
    Molekulargewicht
    120 kDa
    Gen-ID
    4849
    UniProt
    O75175
    Pathways
    Stem Cell Maintenance
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