CDC14B Antikörper

Produktnummer ABIN7112534

Produktdetails anti-CDC14B Antikörper

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC14B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: CDC14 cell division cycle 14 homolog B(S. cerevisiae)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CDC14B

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Andere Bezeichnung: CDC14B (CDC14B Produkte)

Synonyme: CDC14B antikoerper, 2810432N10Rik antikoerper, A530086E13Rik antikoerper, AA472821 antikoerper, CDC14B3 antikoerper, Cdc14B1 antikoerper, Cdc14B2 antikoerper, hCDC14B antikoerper, Dual specificity protein phosphatase CDC14B antikoerper, dual specificity protein phosphatase CDC14B antikoerper, cell division cycle 14B antikoerper, CDC14 cell division cycle 14B antikoerper, Bm1_19115 antikoerper, LOAG_10083 antikoerper, CDC14B antikoerper, cdc14b antikoerper, Cdc14b antikoerper

Hintergrund: Synonyms: Background:Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome(APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

Molekulargewicht: 56 kDa

Gen-ID: 8555

UniProt: O60729