COPS4 Antikörper

Produktnummer ABIN7113044

Produktdetails anti-COPS4 Antikörper

Target: COPS4 (COP9 Signalosome Subunit 4 (COPS4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: COP9 constitutive photomorphogenic homolog subunit 4(Arabidopsis)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu COPS4

Target: COPS4 (COP9 Signalosome Subunit 4 (COPS4))

Andere Bezeichnung: COPS4 (COPS4 Produkte)

Synonyme: CG8725 antikoerper, CH4 antikoerper, Cops4 antikoerper, Csn4 antikoerper, DCH4 antikoerper, Dch4 antikoerper, Dmel\\CG8725 antikoerper, csn4 antikoerper, l(2)k08018 antikoerper, COPS4 antikoerper, SGN4 antikoerper, DKFZp459H0324 antikoerper, AW208976 antikoerper, D5Ertd774e antikoerper, fc90c08 antikoerper, wu:fc90c08 antikoerper, zgc:77137 antikoerper, ATS4 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 14 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 8 antikoerper, COP14 antikoerper, COP9 SIGNALOSOME SUBUNIT 4 antikoerper, CSN4 antikoerper, EMB134 antikoerper, EMBRYO DEFECTIVE 134 antikoerper, FUS4 antikoerper, FUS8 antikoerper, FUSCA 4 antikoerper, FUSCA 8 antikoerper, MBD2.17 antikoerper, MBD2_17 antikoerper, COS41.8 antikoerper, COP9 signalosome subunit 4 antikoerper, COP9 signalosome complex subunit 4 antikoerper, COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) antikoerper, Proteasome component (PCI) domain protein antikoerper, COP9 signalosome subunit 4 L homeolog antikoerper, CSN4 antikoerper, COPS4 antikoerper, CpipJ_CPIJ000966 antikoerper, csn4 antikoerper, Cops4 antikoerper, cops4 antikoerper, COP8 antikoerper, cops4.L antikoerper, csn-4 antikoerper

Hintergrund: Synonyms:CSN4 Background:Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Molekulargewicht: 40, 46 kDa

Gen-ID: 51138

UniProt: Q9BT78

Pathways: Zellzyklus