COPS4 Antikörper
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- Target Alle COPS4 Antikörper anzeigen
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COPS4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- COP9 constitutive photomorphogenic homolog subunit 4(Arabidopsis)
- Isotyp
- IgG
- Top Product
- Discover our top product COPS4 Primärantikörper
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anti-COP9 Signalosome Subunit 4 (COPS4) (AA 1-310) antibody
COPS4 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 53-102) antibodyCOPS4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Schwein, Fledermaus, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 143-192) antibodyCOPS4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Schwein, Zebrafisch (Danio rerio), Huhn, Fledermaus, Hamster, Affe, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (Middle Region) antibodyCOPS4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
- Andere Bezeichnung
- COPS4 (COPS4 Produkte)
- Hintergrund
- Synonyms:CSN4 Background:Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Molekulargewicht
- 40, 46 kDa
- Gen-ID
- 51138
- UniProt
- Q9BT78
- Pathways
- Zellzyklus
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