CEBP antikoerper, CPE-BP1 antikoerper, CPEB antikoerper, AU024112 antikoerper, Cpeb antikoerper, mCPEB antikoerper, CPEB1 antikoerper, cpeb1 antikoerper, ZOR-1 antikoerper, cepb1b antikoerper, fd15c06 antikoerper, wu:fd15c06 antikoerper, zorba antikoerper, cytoplasmic polyadenylation element binding protein 1 antikoerper, hypothetical protein antikoerper, cytoplasmic polyadenylation element binding protein 1 L homeolog antikoerper, cytoplasmic polyadenylation element binding protein 1b antikoerper, cytoplasmic polyadenylation element binding protein 1 S homeolog antikoerper, CPEB1 antikoerper, Cpeb1 antikoerper, cpeb1 antikoerper, LOAG_17395 antikoerper, cpeb1.L antikoerper, cpeb1b antikoerper, cpeb1.S antikoerper
Hintergrund
Synonyms:CPEB Background:Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element(CPE), an uridine-rich sequence element(consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation(By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses(By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation(By similarity). Induces the assembly of stress granules in the absence of stress.