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DDX21 Antikörper

DDX21 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7113335
  • Target Alle DDX21 Antikörper anzeigen
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    Reaktivität
    • 37
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 37
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DDX21 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 13
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    DEAD(Asp-Glu-Ala-Asp) box polypeptide 21
    Isotyp
    IgG
    Top Product
    Discover our top product DDX21 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    Andere Bezeichnung
    DDX21 (DDX21 Produkte)
    Synonyme
    MGC130693 antikoerper, DDX21 antikoerper, cb960 antikoerper, wu:fi30c07 antikoerper, wu:fi34d08 antikoerper, GUA antikoerper, GURDB antikoerper, RH-II/GU antikoerper, RH-II/GuA antikoerper, Ddx21a antikoerper, AI255159 antikoerper, AL022742 antikoerper, D10Ertd645e antikoerper, D10Wsu42e antikoerper, DEAD-box helicase 21 L homeolog antikoerper, DExD-box helicase 21 antikoerper, DEAD-box helicase 21 antikoerper, DEAD (Asp-Glu-Ala-Asp) box helicase 21 antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 antikoerper, ddx21.L antikoerper, DDX21 antikoerper, ddx21 antikoerper, Ddx21 antikoerper
    Hintergrund
    Synonyms: Background:RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase(Pol) I and II: promotes ribosomal RNA(rRNA) processing and transcription from polymerase II(Pol II)(PubMed:25470060). Binds various RNAs, such as rRNAs, snoRNAs, 7SK and, at lower extent, mRNAs(PubMed:25470060). In the nucleolus, localizes to rDNA locus, where it directly binds rRNAs and snoRNAs, and promotes rRNA transcription, processing and modification. Required for rRNA 2'-O-methylation, possibly by promoting the recruitment of late-acting snoRNAs SNORD56 and SNORD58 with pre-ribosomal complexes(PubMed:25470060, PubMed:25477391). In the nucleoplasm, binds 7SK RNA and is recruited to the promoters of Pol II-transcribed genes: acts by facilitating the release of P-TEFb from inhibitory 7SK snRNP in a manner that is dependent on its helicase activity, thereby promoting transcription of its target genes(PubMed:25470060). Functions as cofactor for JUN-activated transcription: required for phosphorylation of JUN at 'Ser-77'(PubMed:11823437, PubMed:25260534). Can unwind double-stranded RNA(helicase) and can fold or introduce a secondary structure to a single-stranded RNA(foldase)(PubMed:9461305). Involved in rRNA processing(PubMed:14559904, PubMed:18180292).
    Molekulargewicht
    87 kDa
    Gen-ID
    9188
    UniProt
    Q9NR30
    Pathways
    SARS-CoV-2 Protein Interaktom
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