ECD/SGT1 Antikörper
-
- Target Alle ECD/SGT1 (ECD) Antikörper anzeigen
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ECD/SGT1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- ecdysoneless homolog(Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product ECD Primärantikörper
-
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibody
ECD Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1A11 unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-300) antibodyECD Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibodyECD Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (C-Term) antibodyECD Reaktivität: Human, Ziege, Pferd, Rind (Kuh), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 72-121) antibodyECD Reaktivität: Human, Ziege, Pferd, Kaninchen, Rind (Kuh), Schwein, Hund, Meerschweinchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
-
- Target
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
- Andere Bezeichnung
- ECD (ECD Produkte)
- Hintergrund
- Synonyms: Background:Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP(PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes(PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins(PubMed:19640839). The cell cycle-regulating function may depend on its RUVBL1-mediated association with the R2TP complex(PubMed:26711270). May play a role in regulation of pre-mRNA splicing(PubMed:24722212).
- Molekulargewicht
- 73 kDa
- Gen-ID
- 11319
- UniProt
- O95905
- Pathways
- Regulation of Carbohydrate Metabolic Process
-
