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Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) Antikörper

EIF3M Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1A4 unconjugated
Produktnummer ABIN7113959
  • Target Alle Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) Antikörper anzeigen
    Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
    Reaktivität
    • 32
    • 23
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 1
    Maus
    Klonalität
    • 32
    Monoklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 27
    • 13
    • 11
    • 11
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Aufreinigung
    Protein A+G purification
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    eukaryotic translation initiation factor 3, subunit M
    Klon
    1A4
    Isotyp
    IgG1
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  • Applikationshinweise
    WB: 1:500-1:2000, IF: 1:10-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
    Andere Bezeichnung
    EIF3M (EIF3M Produkte)
    Substanzklasse
    Viral Protein
    Hintergrund
    Synonyms:HFLB5, PCID1 Background:Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2).
    Molekulargewicht
    43 kDa
    Gen-ID
    10480
    UniProt
    Q7L2H7
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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