Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) Antikörper
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- Target Alle Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) Antikörper anzeigen
- Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Aufreinigung
- Protein A+G purification
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- eukaryotic translation initiation factor 3, subunit M
- Klon
- 1A4
- Isotyp
- IgG1
- Top Product
- Discover our top product EIF3M Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IF: 1:10-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
- Andere Bezeichnung
- EIF3M (EIF3M Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
- Synonyms:HFLB5, PCID1 Background:Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2).
- Molekulargewicht
- 43 kDa
- Gen-ID
- 10480
- UniProt
- Q7L2H7
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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