ERCC6 Antikörper

Produktnummer ABIN7113989

Produktdetails anti-ERCC6 Antikörper

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ERCC6

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Andere Bezeichnung: ERCC6 (ERCC6 Produkte)

Synonyme: ARMD5 antikoerper, CKN2 antikoerper, COFS antikoerper, COFS1 antikoerper, CSB antikoerper, RAD26 antikoerper, UVSS1 antikoerper, 4732403I04 antikoerper, C130058G22Rik antikoerper, ercc6 antikoerper, Ercc6 antikoerper, ERCC excision repair 6, chromatin remodeling factor antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 6 antikoerper, excision repair cross-complementation group 6 antikoerper, DNA excision repair protein ERCC-6 antikoerper, ERCC6 antikoerper, Ercc6 antikoerper, ercc6 antikoerper, LOC100719487 antikoerper

Hintergrund: Synonyms:CSB Background:Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

Molekulargewicht: 150kd

Gen-ID: 2074

UniProt: Q03468

Pathways: DNA Reparatur, Chromatin Binding