EXD1 Antikörper
EXD1
Reaktivität: Human, Ratte, Maus
WB, IF, ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
-
- Target Alle EXD1 Antikörper anzeigen
- EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))
- Reaktivität
- Human, Ratte, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser EXD1 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- exonuclease 3'-5' domain containing 1
- Isotyp
- IgG
-
-
- Applikationshinweise
- WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
-
- Target
- EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))
- Andere Bezeichnung
- EXD1 (EXD1 Produkte)
- Synonyme
- EXDL1 antikoerper, Exdl1 antikoerper, RGD1561009 antikoerper, 4932702D22Rik antikoerper, exd1 antikoerper, exonuclease 3'-5' domain containing 1 antikoerper, EXD1 antikoerper, Exd1 antikoerper, exd1 antikoerper
- Hintergrund
- Synonyms:EXDL1 Background:RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).
- Molekulargewicht
- 36 kDa
- Gen-ID
- 161829
- UniProt
- Q8NHP7
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