FBXO2 Antikörper
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- Target Alle FBXO2 Antikörper anzeigen
- FBXO2 (F-Box Protein 2 (FBXO2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBXO2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- F-box protein 2
- Isotyp
- IgG
- Top Product
- Discover our top product FBXO2 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- FBXO2 (F-Box Protein 2 (FBXO2))
- Andere Bezeichnung
- FBXO2 (FBXO2 Produkte)
- Synonyme
- FBG1 antikoerper, FBX2 antikoerper, Fbs1 antikoerper, NFB42 antikoerper, OCP1 antikoerper, Fbs2 antikoerper, Prpl4 antikoerper, F-box protein 2 antikoerper, FBXO2 antikoerper, Fbxo2 antikoerper
- Hintergrund
- Synonyms:FBX2 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway(ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type(By similarity).
- Molekulargewicht
- 33-40 kDa
- Gen-ID
- 26232
- UniProt
- Q9UK22
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