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FBXO2 Antikörper

FBXO2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7114045
  • Target Alle FBXO2 Antikörper anzeigen
    FBXO2 (F-Box Protein 2 (FBXO2))
    Reaktivität
    • 28
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 4
    Kaninchen
    Klonalität
    • 40
    • 2
    Polyklonal
    Konjugat
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FBXO2 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 18
    • 14
    • 13
    • 13
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    F-box protein 2
    Isotyp
    IgG
    Top Product
    Discover our top product FBXO2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    FBXO2 (F-Box Protein 2 (FBXO2))
    Andere Bezeichnung
    FBXO2 (FBXO2 Produkte)
    Synonyme
    FBG1 antikoerper, FBX2 antikoerper, Fbs1 antikoerper, NFB42 antikoerper, OCP1 antikoerper, Fbs2 antikoerper, Prpl4 antikoerper, F-box protein 2 antikoerper, FBXO2 antikoerper, Fbxo2 antikoerper
    Hintergrund
    Synonyms:FBX2 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway(ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type(By similarity).
    Molekulargewicht
    33-40 kDa
    Gen-ID
    26232
    UniProt
    Q9UK22
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