F-Box Protein 3 Antikörper

Produktnummer ABIN7114048

Produktdetails anti-F-Box Protein 3 Antikörper

Target: F-Box Protein 3 (FBXO3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F-Box Protein 3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: F-box protein 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu F-Box Protein 3

Target: F-Box Protein 3 (FBXO3)

Andere Bezeichnung: FBXO3 (FBXO3 Produkte)

Synonyme: FBA antikoerper, FBX3 antikoerper, 1200002G09Rik antikoerper, 1700026K02Rik antikoerper, AI046358 antikoerper, Fba antikoerper, zgc:112485 antikoerper, DKFZp459H187 antikoerper, F-box protein 3 antikoerper, F-box protein 3 S homeolog antikoerper, FBXO3 antikoerper, Fbxo3 antikoerper, fbxo3.S antikoerper, fbxo3 antikoerper

Hintergrund: Synonyms:FBX3 Background:Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Molekulargewicht: 48-50kd

Gen-ID: 26273

UniProt: Q9UK99