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FBXO9 Antikörper

FBXO9 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN7114056

Datenblatt (PDF)

Target Alle FBXO9 Antikörper anzeigen

FBXO9 (F-Box Protein 9 (FBXO9))
Reaktivität
37

19

15

10

2

2

2

2

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
48

4
Kaninchen
Passende Sekundärantikörper
Klonalität
50

2
Polyklonal
Konjugat
20

5

4

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser FBXO9 Antikörper ist unkonjugiert
Applikation
35

24

14

13

9

6

6

5

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung

Immunogen affinity purified

Reinheit

≥95 % as determined by SDS-PAGE

Immunogen

F-box protein 9

Isotyp

IgG

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anti-F-Box Protein 9 (FBXO9) (AA 13-111) antibody
FBXO9 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 338-447) antibody
FBXO9 Reaktivität: Human ELISA, IHC (p) Wirt: Maus Monoclonal 1G12 unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 1-437) antibody
FBXO9 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) (Middle Region) antibody
FBXO9 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Schwein, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) antibody
FBXO9 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 346-373), (C-Term) antibody
FBXO9 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB26852 unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 431-447) antibody
FBXO9 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 179-228) antibody
FBXO9 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Pferd, Schwein, Kaninchen, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 346-373), (C-Term) antibody
FBXO9 Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-F-Box Protein 9 (FBXO9) (AA 13-111) antibody (HRP)
FBXO9 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP

Applikationshinweise

WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

-20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit

12 months
Target

FBXO9 (F-Box Protein 9 (FBXO9))

Andere Bezeichnung

FBXO9 (FBXO9 Produkte)

Hintergrund

Synonyms:FBX9, VCIA1 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Molekulargewicht

52 kDa

Gen-ID

26268

UniProt

Q9UK97