CCDC98 Antikörper

Produktnummer ABIN7114081

Produktdetails anti-CCDC98 Antikörper

Target: CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC98 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: family with sequence similarity 175, member A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2400, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CCDC98

Target: CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))

Andere Bezeichnung: FAM175A (FAM175A Produkte)

Synonyme: CCDC98 antikoerper, abra1 antikoerper, ccdc98 antikoerper, fam175a antikoerper, ABRA1 antikoerper, 3830405G04Rik antikoerper, 5630400M01Rik antikoerper, AI506069 antikoerper, AL024423 antikoerper, AV118690 antikoerper, Ccdc98 antikoerper, RGD1305287 antikoerper, zgc:103522 antikoerper, abraxas 1, BRCA1 A complex subunit antikoerper, Coiled-coil domain-containing protein 98 antikoerper, BRCA1 A complex subunit antikoerper, family with sequence similarity 175 member A antikoerper, abraxas 2a, BRISC complex subunit antikoerper, abraxas 1, BRCA1 A complex subunit S homeolog antikoerper, ABRAXAS1 antikoerper, abraxas1 antikoerper, Abraxas1 antikoerper, FAM175A antikoerper, abraxas2a antikoerper, abraxas1.S antikoerper

Hintergrund: Synonyms:ABRA1, CCDC98 Background:Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Molekulargewicht: 46 kDa

Gen-ID: 84142

UniProt: Q6UWZ7

Pathways: DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus