Glutaredoxin 2 Antikörper
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- Target Alle Glutaredoxin 2 (GRX2) Antikörper anzeigen
- Glutaredoxin 2 (GRX2)
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Glutaredoxin 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- glutaredoxin 2
- Isotyp
- IgG
- Top Product
- Discover our top product GRX2 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- Glutaredoxin 2 (GRX2)
- Andere Bezeichnung
- GLRX2 (GRX2 Produkte)
- Synonyme
- ECK1049 antikoerper, JW1051 antikoerper, CGI-133 antikoerper, GRX2 antikoerper, 1700010P22Rik antikoerper, AI645710 antikoerper, Grx2 antikoerper, glutaredoxin 2 (Grx2) antikoerper, glutaredoxin Grx2 antikoerper, thioredoxin antikoerper, glutaredoxin 2 antikoerper, glutaredoxin 2 (thioltransferase) antikoerper, grxB antikoerper, grx2 antikoerper, AF_RS10790 antikoerper, GLRX2 antikoerper, Glrx2 antikoerper
- Hintergrund
- Synonyms:GRX2 Background:Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
- Molekulargewicht
- 16 kDa
- Gen-ID
- 51022
- UniProt
- Q9NS18
- Pathways
- Cell RedoxHomeostasis
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