LE antikoerper, 2010205O06Rik antikoerper, AU040608 antikoerper, BLOC-3 antikoerper, C130020P05Rik antikoerper, le antikoerper, mKIAA1667 antikoerper, HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 antikoerper, HPS4 antikoerper, Hps4 antikoerper
Hintergrund
Synonyms:KIAA1667 Background:Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).