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IPO13 Antikörper

IPO13 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7115209
  • Target Alle IPO13 Antikörper anzeigen
    IPO13 (Importin 13 (IPO13))
    Reaktivität
    • 19
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IPO13 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    importin 13
    Isotyp
    IgG
    Top Product
    Discover our top product IPO13 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    IPO13 (Importin 13 (IPO13))
    Andere Bezeichnung
    IPO13 (IPO13 Produkte)
    Synonyme
    3R23 antikoerper, CG 7212 antikoerper, CG7212 antikoerper, Dmel\\CG7212 antikoerper, Imp13 antikoerper, imp13 antikoerper, sd-5 antikoerper, DDBDRAFT_0205767 antikoerper, DDBDRAFT_0304414 antikoerper, DDB_0205767 antikoerper, DDB_0304414 antikoerper, DDBDRAFT_0191787 antikoerper, DDBDRAFT_0304413 antikoerper, DDB_0191787 antikoerper, DDB_0304413 antikoerper, IMP13 antikoerper, KAP13 antikoerper, LGL2 antikoerper, RANBP13 antikoerper, Kap13 antikoerper, Ranbp13 antikoerper, Lgl2 antikoerper, DKFZp459H088 antikoerper, cadmus antikoerper, importin 13 antikoerper, cdm antikoerper, IPO13 antikoerper, AFUA_5G08060 antikoerper, ANI_1_1340034 antikoerper, AOR_1_1272114 antikoerper, ipo13B antikoerper, ipo13A antikoerper, ipo13 antikoerper, Ipo13 antikoerper
    Hintergrund
    Synonyms:KIAA0724, RANBP13 Background:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.
    Molekulargewicht
    97kd
    Gen-ID
    9670
    UniProt
    O94829
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Protein targeting to Nucleus
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