INSIG1 Antikörper
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- Target Alle INSIG1 Antikörper anzeigen
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser INSIG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- insulin induced gene 1
- Isotyp
- IgG
- Top Product
- Discover our top product INSIG1 Primärantikörper
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anti-Insulin Induced Gene 1 (INSIG1) (AA 1-87) antibody
INSIG1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibodyINSIG1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB21689 unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibodyINSIG1 Reaktivität: Human, Maus WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 63-112) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Hund, Schwein, Affe, Hamster, Xenopus laevis, Fledermaus, Huhn WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Schaf, Hund, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 71-120) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Ziege, Schaf, Schwein, Hamster, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reaktivität: Human, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Schaf, Hund, Schwein, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- Andere Bezeichnung
- INSIG1 (INSIG1 Produkte)
- Synonyme
- cl-6 antikoerper, cl6 antikoerper, CL-6 antikoerper, CL6 antikoerper, fb55a03 antikoerper, fi35b10 antikoerper, wu:fb55a03 antikoerper, wu:fi35b10 antikoerper, zgc:55439 antikoerper, 1810013C12Rik antikoerper, Insig-1 antikoerper, INSIG-1 antikoerper, insulin induced gene 1 antikoerper, insulin induced gene 1 L homeolog antikoerper, INSIG1 antikoerper, insig1 antikoerper, insig1.L antikoerper, Insig1 antikoerper
- Hintergrund
- Synonyms:CL 6, INSIG 1, INSIG1, insulin induced gene 1, Insulin induced gene 1 protein Background:Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation(ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.
- Molekulargewicht
- 28-31, 66-70 kDa
- Gen-ID
- 3638
- UniProt
- O15503
- Pathways
- ER-Nucleus Signaling
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