INSIG2 Antikörper

Produktnummer ABIN7115275

Produktdetails anti-INSIG2 Antikörper

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: insulin induced gene 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Andere Bezeichnung: INSIG2 (INSIG2 Produkte)

Synonyme: MGC82156 antikoerper, INSIG-2 antikoerper, 2900053I11Rik antikoerper, C730043J18Rik antikoerper, Insig-2 antikoerper, insulin induced gene 2 antikoerper, insulin induced gene 2 L homeolog antikoerper, insig2 antikoerper, insig2.L antikoerper, INSIG2 antikoerper, Insig2 antikoerper

Hintergrund: Synonyms: Background:Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

Molekulargewicht: 30 kDa

Gen-ID: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling