Inversin Antikörper
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- Target Alle Inversin (INVS) Antikörper anzeigen
- Inversin (INVS)
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Inversin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- inversin
- Isotyp
- IgG
- Top Product
- Discover our top product INVS Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- Inversin (INVS)
- Andere Bezeichnung
- INVS (INVS Produkte)
- Synonyme
- invs-a antikoerper, INVS antikoerper, MGC140477 antikoerper, inv antikoerper, NPH2 antikoerper, NPHP2 antikoerper, INV antikoerper, Nphp2 antikoerper, RGD1563359 antikoerper, wu:fe47e11 antikoerper, inversin S homeolog antikoerper, inversin antikoerper, Inversin antikoerper, invs.S antikoerper, INVS antikoerper, Bm1_38710 antikoerper, PTRG_09181 antikoerper, EAMY_RS33690 antikoerper, LOAG_11716 antikoerper, invs antikoerper, Invs antikoerper
- Hintergrund
- Synonyms:INV, NPHP2 Background:Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled(DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8(By similarity). Does not seem to be strictly required for ciliogenesis(By similarity).
- Molekulargewicht
- 110-115 kDa
- Gen-ID
- 27130
- UniProt
- Q9Y283
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