IQCB1 Antikörper

Produktnummer ABIN7115509

Produktdetails anti-IQCB1 Antikörper

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQCB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: IQ motif containing B1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Andere Bezeichnung: NPHP5,IQCB1 (IQCB1 Produkte)

Synonyme: piq antikoerper, nphp5 antikoerper, slsn5 antikoerper, MGC81507 antikoerper, IQCB1 antikoerper, zgc:101792 antikoerper, MGC146213 antikoerper, 6820449I09Rik antikoerper, AV128382 antikoerper, NPHP5 antikoerper, PIQ antikoerper, SLSN5 antikoerper, IQ motif containing B1 antikoerper, IQ motif containing B1 L homeolog antikoerper, IQ calmodulin-binding motif containing 1 antikoerper, Iqcb1 antikoerper, iqcb1.L antikoerper, IQCB1 antikoerper, iqcb1 antikoerper

Hintergrund: Synonyms:IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, NPHP5, PIQ, SLSN5 Background:IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

UniProt: Q15051