IWS1 Antikörper
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- Target Alle IWS1 Produkte
- IWS1 (IWS1 Homolog (IWS1))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IWS1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- IWS1 homolog(S. cerevisiae)
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- IWS1 (IWS1 Homolog (IWS1))
- Andere Bezeichnung
- IWS1 (IWS1 Produkte)
- Synonyme
- 1700069O15Rik antikoerper, 3000008H23 antikoerper, AL117927 antikoerper, AW214353 antikoerper, RGD1304762 antikoerper, IWS1, SUPT6H interacting protein antikoerper, IWS1, SUPT6 interacting protein antikoerper, IWS1 antikoerper, Iws1 antikoerper
- Hintergrund
- Synonyms:IWS1L Background:Transcription factor which plays a key role in defining the composition of the RNA polymerase II(RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain(CTD) of the RNAPII subunit RPB1(POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors(ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes(such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
- Molekulargewicht
- 116-120 kDa
- Gen-ID
- 55677
- UniProt
- Q96ST2
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