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IWS1 Antikörper

IWS1 Reaktivität: Human, Ratte, Maus WB, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7115537
  • Target Alle IWS1 Produkte
    IWS1 (IWS1 Homolog (IWS1))
    Reaktivität
    • 17
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 17
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IWS1 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    IWS1 homolog(S. cerevisiae)
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    IWS1 (IWS1 Homolog (IWS1))
    Andere Bezeichnung
    IWS1 (IWS1 Produkte)
    Synonyme
    1700069O15Rik antikoerper, 3000008H23 antikoerper, AL117927 antikoerper, AW214353 antikoerper, RGD1304762 antikoerper, IWS1, SUPT6H interacting protein antikoerper, IWS1, SUPT6 interacting protein antikoerper, IWS1 antikoerper, Iws1 antikoerper
    Hintergrund
    Synonyms:IWS1L Background:Transcription factor which plays a key role in defining the composition of the RNA polymerase II(RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain(CTD) of the RNAPII subunit RPB1(POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors(ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes(such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
    Molekulargewicht
    116-120 kDa
    Gen-ID
    55677
    UniProt
    Q96ST2
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