zgc:76933 antikoerper, 1810045K06Rik antikoerper, D330008A20 antikoerper, mKIAA0469 antikoerper, RGD1305863 antikoerper, kelch-like family member 21 antikoerper, kelch like family member 21 antikoerper, kelch like family member 21 L homeolog antikoerper, kelch-like 21 antikoerper, klhl21 antikoerper, KLHL21 antikoerper, klhl21.L antikoerper, Klhl21 antikoerper
Hintergrund
Synonyms:KIAA0469 Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex(CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.