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KIDINS220 Antikörper

KIDINS220 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7115686
  • Target Alle KIDINS220 Antikörper anzeigen
    KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
    Reaktivität
    • 38
    • 12
    • 11
    • 1
    Human, Ratte, Maus
    Wirt
    • 39
    • 10
    Kaninchen
    Klonalität
    • 39
    • 10
    Polyklonal
    Konjugat
    • 22
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser KIDINS220 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 17
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    kinase D-interacting substrate, 220kDa
    Isotyp
    IgG
    Top Product
    Discover our top product KIDINS220 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
    Andere Bezeichnung
    KIDINS220 (KIDINS220 Produkte)
    Synonyme
    ARMS antikoerper, fj35h03 antikoerper, kidins220 antikoerper, zgc:63531 antikoerper, dZ119J18.2 antikoerper, wu:fj35h03 antikoerper, 3110039L19Rik antikoerper, AI194387 antikoerper, AI316525 antikoerper, C330002I19Rik antikoerper, mKIAA1250 antikoerper, kinase D interacting substrate 220 antikoerper, kinase D-interacting substrate 220 antikoerper, kinase D-interacting substrate 220b antikoerper, kinase D-interacting substrate 220kDa antikoerper, KIDINS220 antikoerper, Kidins220 antikoerper, kidins220b antikoerper
    Hintergrund
    Synonyms:ARMS, KIAA1250 Background:Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor(NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration(By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
    Molekulargewicht
    186-197 kDa
    Gen-ID
    57498
    UniProt
    Q9ULH0
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