LRRC8D Antikörper

Produktnummer ABIN7115814

Produktdetails anti-LRRC8D Antikörper

Target: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC8D Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: leucine rich repeat containing 8 family, member D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu LRRC8D

Target: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Andere Bezeichnung: LRRC8D (LRRC8D Produkte)

Synonyme: LRRC5 antikoerper, 2810473G09Rik antikoerper, 4930525N13Rik antikoerper, A930019F03 antikoerper, Lrrc5 antikoerper, LRRC8D antikoerper, DKFZp469O1725 antikoerper, lrrc8d antikoerper, zgc:153223 antikoerper, leucine rich repeat containing 8 VRAC subunit D antikoerper, leucine rich repeat containing 8D antikoerper, leucine rich repeat containing 8 family member D antikoerper, leucine rich repeat containing 8 VRAC subunit Db antikoerper, LRRC8D antikoerper, Lrrc8d antikoerper, lrrc8d antikoerper, lrrc8db antikoerper

Hintergrund: Synonyms:LRRC5 Background:Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition(PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin(PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell(PubMed:24782309).

Molekulargewicht: 98-120 kDa

Gen-ID: 55144

UniProt: Q7L1W4