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MSL1 Antikörper

MSL1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7116032
  • Target Alle MSL1 Antikörper anzeigen
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    Reaktivität
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MSL1 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    male-specific lethal 1 homolog(Drosophila)
    Isotyp
    IgG
    Top Product
    Discover our top product MSL1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    Andere Bezeichnung
    MSL1 (MSL1 Produkte)
    Synonyme
    MSL-1 antikoerper, hMSL1 antikoerper, 2810017F12Rik antikoerper, 4121402D02Rik antikoerper, 4930463F05Rik antikoerper, AA682082 antikoerper, Msl-1 antikoerper, male specific lethal 1 homolog antikoerper, male-specific lethal 1 homolog (Drosophila) antikoerper, MSL1 antikoerper, Msl1 antikoerper
    Hintergrund
    Synonyms:MSL1L1 Background:Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
    Molekulargewicht
    67 kDa
    Gen-ID
    339287
    UniProt
    Q68DK7
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