MAML1 Antikörper
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- Target Alle MAML1 Antikörper anzeigen
- MAML1 (Mastermind-Like 1 (MAML1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAML1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- mastermind-like 1(Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product MAML1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- MAML1 (Mastermind-Like 1 (MAML1))
- Andere Bezeichnung
- MAML1 (MAML1 Produkte)
- Synonyme
- mam1 antikoerper, mam-1 antikoerper, xmam1 antikoerper, MAML1 antikoerper, AI644666 antikoerper, AW743257 antikoerper, D930008C07Rik antikoerper, Mam-1 antikoerper, Mam1 antikoerper, mKIAA0200 antikoerper, mastermind like transcriptional coactivator 1 L homeolog antikoerper, mastermind like transcriptional coactivator 1 antikoerper, mastermind like 1 (Drosophila) antikoerper, mastermind-like transcriptional coactivator 1 antikoerper, maml1.L antikoerper, MAML1 antikoerper, Maml1 antikoerper
- Hintergrund
- Synonyms:KIAA0200 Background:Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
- Molekulargewicht
- 108-120kd
- Gen-ID
- 9794
- UniProt
- Q92585
- Pathways
- Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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