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MEIS2 Antikörper

MEIS2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7116144
  • Target Alle MEIS2 Antikörper anzeigen
    MEIS2 (Meis Homeobox 2 (MEIS2))
    Reaktivität
    • 39
    • 16
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Human, Maus, Ratte
    Wirt
    • 34
    • 5
    • 1
    Kaninchen
    Klonalität
    • 27
    • 13
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MEIS2 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 17
    • 11
    • 11
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    Meis homeobox 2
    Isotyp
    IgG
    Top Product
    Discover our top product MEIS2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    MEIS2 (Meis Homeobox 2 (MEIS2))
    Andere Bezeichnung
    MEIS2 (MEIS2 Produkte)
    Hintergrund
    Synonyms:MRG1 Background:Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex(PTF1) bound to the enhancer A element, MEIS2 is not involved in complex DNA-binding. Probably in complex with PBX1, is involved in transcriptional regulation by KLF4. Isoform 3 and isoform 4 can bind to a EPHA8 promoter sequence containing the DNA motif 5'-CGGTCA-3', in cooperation with a PBX protein(such as PBX2) is proposed to be involved in the transcriptional activation of EPHA8 in the developing midbrain. May be involved in regulation of myeloid differentiation. Can bind to the DNA sequence 5'-TGACAG-3'in the activator ACT sequence of the D(1A) dopamine receptor(DRD1) promoter and activate DRD1 transcription, isoform 5 cannot activate DRD1 transcription.
    Molekulargewicht
    56kd
    Gen-ID
    4212
    UniProt
    O14770
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