CG11098 antikoerper, Dmel\\CG11098 antikoerper, TANGO1 antikoerper, MIA3 antikoerper, 9130229H14Rik antikoerper, A930039G15Rik antikoerper, AU022327 antikoerper, B230399H06Rik antikoerper, C80126 antikoerper, Gm1525 antikoerper, Tango antikoerper, ARNT antikoerper, D320 antikoerper, TANGO antikoerper, UNQ6077 antikoerper, Transport and Golgi organization 1 antikoerper, MIA family member 3, ER export factor antikoerper, melanoma inhibitory activity family, member 3 antikoerper, melanoma inhibitory activity protein 3 antikoerper, melanoma inhibitory activity family member 3 antikoerper, melanoma inhibitory activity 3 antikoerper, Tango1 antikoerper, MIA3 antikoerper, LOC100055507 antikoerper, mia3 antikoerper, Mia3 antikoerper
Hintergrund
Synonyms:KIAA0268, TANGO, TANGO1 Background:Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).