Rkhd2 antikoerper, RKHD2 antikoerper, rkhd2 antikoerper, bm-013 antikoerper, rnf194 antikoerper, MEX-3C antikoerper, RNF194 antikoerper, A130001D14Rik antikoerper, BC035207 antikoerper, BM-013 antikoerper, mex-3 RNA binding family member C antikoerper, mex3 RNA binding family member C antikoerper, Mex3c antikoerper, MEX3C antikoerper, mex3c antikoerper
Hintergrund
Synonyms:RKHD2, RNF194 Background:E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.