MICAL2 Antikörper
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- Target Alle MICAL2 Antikörper anzeigen
- MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MICAL2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- microtubule associated monoxygenase, calponin and LIM domain containing 2
- Isotyp
- IgG
- Top Product
- Discover our top product MICAL2 Primärantikörper
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anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2) (AA 1-495) antibody
MICAL2 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2) (AA 55-83), (N-Term) antibodyMICAL2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB18640 unconjugated
anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2) (C-Term) antibodyMICAL2 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Hund, Schwein, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC: 1:20-1:200, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))
- Andere Bezeichnung
- MICAL2 (MICAL2 Produkte)
- Synonyme
- MICAL-2 antikoerper, MICAL2PV1 antikoerper, MICAL2PV2 antikoerper, 5330438E18Rik antikoerper, 9530064J02 antikoerper, mKIAA0750 antikoerper, RGD1311773 antikoerper, microtubule associated monooxygenase, calponin and LIM domain containing 2 antikoerper, MICAL2 antikoerper, Mical2 antikoerper
- Hintergrund
- Synonyms:KIAA0750, MICAL2PV1, MICAL2PV2 Background:Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
- Molekulargewicht
- 95, 112 kDa
- Gen-ID
- 9645
- UniProt
- O94851
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