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MACF1 Antikörper

MACF1 Reaktivität: Human, Maus, Ratte ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7116291
  • Target Alle MACF1 Antikörper anzeigen
    MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 8
    • 2
    Kaninchen
    Klonalität
    • 9
    • 1
    Polyklonal
    Konjugat
    • 5
    • 2
    • 2
    • 1
    Dieser MACF1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 6
    • 3
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    microtubule-actin crosslinking factor 1
    Isotyp
    IgG
    Top Product
    Discover our top product MACF1 Primärantikörper
  • Applikationshinweise
    IHC: 1:20-1:200, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
    Andere Bezeichnung
    MACF1 (MACF1 Produkte)
    Synonyme
    ABP620 antikoerper, ACF7 antikoerper, MACF antikoerper, OFC4 antikoerper, Acf7 antikoerper, Aclp7 antikoerper, R74989 antikoerper, mKIAA0465 antikoerper, MACF1 antikoerper, fc46g01 antikoerper, wu:fc46g01 antikoerper, si:rp71-45k5.7 antikoerper, acf7 antikoerper, macf antikoerper, ofc4 antikoerper, abp620 antikoerper, DKFZp469K2016 antikoerper, Kiaa0754 antikoerper, mKIAA0754 antikoerper, microtubule-actin crosslinking factor 1 antikoerper, microtubule-actin crosslinking factor 1a antikoerper, microtubule-actin cross-linking factor 1 antikoerper, dual specificity protein kinase CLK3 antikoerper, microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 antikoerper, KIAA0754 antikoerper, RIKEN cDNA D830031N03 gene antikoerper, MACF1 antikoerper, Macf1 antikoerper, macf1a antikoerper, macf1 antikoerper, LOC100175356 antikoerper, LOC100514848 antikoerper, LOC100550622 antikoerper, KIAA0754 antikoerper, D830031N03Rik antikoerper
    Hintergrund
    Synonyms:ABP620, ACF7, KIAA0465, KIAA1251 Background:Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex(composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions(FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells(By similarity).
    Molekulargewicht
    83 kDa
    Gen-ID
    23499
    UniProt
    Q9UPN3
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