C20orf72 Antikörper
MGME1
Reaktivität: Human, Maus
ELISA, WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
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- Target Alle C20orf72 (MGME1) Produkte
- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C20orf72 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- chromosome 20 open reading frame 72
- Isotyp
- IgG
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anti-Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) (AA 81-260) antibody
MGME1 Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) antibodyMGME1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
- Andere Bezeichnung
- MGME1 (MGME1 Produkte)
- Synonyme
- C20orf72 antikoerper, DDK1 antikoerper, MTDPS11 antikoerper, bA504H3.4 antikoerper, mitochondrial genome maintenance exonuclease 1 antikoerper, MGME1 antikoerper
- Hintergrund
- Synonyms:C20orf72, DDK1 Background:Metal-dependent single-stranded DNA(ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA(mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine(5hmC)-containing DNA in stem cells.
- Molekulargewicht
- 36-39 kDa
- Gen-ID
- 92667
- UniProt
- Q9BQP7
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