MMS19 Antikörper
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- Target Alle MMS19 Antikörper anzeigen
- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MMS19 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- MMS19 nucleotide excision repair homolog(S. cerevisiae)
- Isotyp
- IgG
- Top Product
- Discover our top product MMS19 Primärantikörper
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anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (AA 1-293) antibody
MMS19 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (AA 851-950) antibodyMMS19 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (Internal Region) antibodyMMS19 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (AA 411-437) antibodyMMS19 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38896 unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
- Andere Bezeichnung
- MMS19 (MMS19 Produkte)
- Hintergrund
- Synonyms:MMS19L Background:Key component of the cytosolic iron-sulfur protein assembly(CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair(NER) and RNA polymerase II(POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor(ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
- Molekulargewicht
- 103 kDa
- Gen-ID
- 64210
- UniProt
- Q96T76
- Pathways
- Nuclear Hormone Receptor Binding
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