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NGEF Antikörper

NGEF Reaktivität: Human, Maus WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7116830
  • Target Alle NGEF Antikörper anzeigen
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Reaktivität
    • 41
    • 40
    • 33
    • 3
    • 3
    • 3
    • 3
    Human, Maus
    Wirt
    • 47
    • 1
    Kaninchen
    Klonalität
    • 47
    • 1
    Polyklonal
    Konjugat
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NGEF Antikörper ist unkonjugiert
    Applikation
    • 38
    • 26
    • 26
    • 10
    • 6
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    neuronal guanine nucleotide exchange factor
    Isotyp
    IgG
    Top Product
    Discover our top product NGEF Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Andere Bezeichnung
    NGEF (NGEF Produkte)
    Synonyme
    Ephexin-1 antikoerper, ARHGEF27 antikoerper, EPHEXIN antikoerper, Tims2 antikoerper, ephexin antikoerper, Besh3 antikoerper, ephexin-1 antikoerper, neuronal guanine nucleotide exchange factor antikoerper, NGEF antikoerper, Ngef antikoerper
    Hintergrund
    Synonyms: Background:Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension(By similarity).
    Molekulargewicht
    75 kDa
    Gen-ID
    25791
    UniProt
    Q8N5V2
    Pathways
    Neurotrophin Signalübertragung
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