OTUD7B Antikörper
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- Target Alle OTUD7B Antikörper anzeigen
- OTUD7B (OTU Domain Containing 7B (OTUD7B))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OTUD7B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- OTU domain containing 7B
- Isotyp
- IgG
- Top Product
- Discover our top product OTUD7B Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- OTUD7B (OTU Domain Containing 7B (OTUD7B))
- Andere Bezeichnung
- OTUD7B (OTUD7B Produkte)
- Synonyme
- OTUD7B antikoerper, ZA20D1 antikoerper, za20d1 antikoerper, zgc:152772 antikoerper, cezanne antikoerper, CEZANNE antikoerper, 2900060B22Rik antikoerper, 4930463P07Rik antikoerper, AI462125 antikoerper, Trabid2 antikoerper, Za20d1 antikoerper, RGD1308111 antikoerper, OTU deubiquitinase 7B antikoerper, OTU domain containing 7B antikoerper, OTUD7B antikoerper, otud7b antikoerper, Otud7b antikoerper
- Hintergrund
- Synonyms:ZA20D1 Background:Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections. Mediates deubiquitination of EGFR. Has deubiquitinating activity toward 'Lys-11', 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. In vitro, has preference for 'Lys-11'-linked polyubiquitin chains, however such data are unsure in vivo. Hydrolyzes both linear and branched forms of polyubiquitin.
- Molekulargewicht
- 100 kDa
- Gen-ID
- 56957
- UniProt
- Q6GQQ9
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