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OSBP Antikörper

OSBP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7117171
  • Target Alle OSBP Antikörper anzeigen
    OSBP (Oxysterol Binding Protein (OSBP))
    Reaktivität
    • 20
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 16
    • 3
    • 1
    Kaninchen
    Klonalität
    • 17
    • 3
    Polyklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    Dieser OSBP Antikörper ist unkonjugiert
    Applikation
    • 15
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    oxysterol binding protein
    Isotyp
    IgG
    Top Product
    Discover our top product OSBP Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    OSBP (Oxysterol Binding Protein (OSBP))
    Andere Bezeichnung
    OSBP (OSBP Produkte)
    Synonyme
    CG6708 antikoerper, Dmel\\CG6708 antikoerper, OSBP-Dm antikoerper, osbp antikoerper, OSBP1 antikoerper, 1110018F06Rik antikoerper, AW559088 antikoerper, mKIAA4220 antikoerper, Oxysterol binding protein antikoerper, oxysterol binding protein antikoerper, Osbp antikoerper, OSBP antikoerper
    Hintergrund
    Synonyms:OSBP1 Background:Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate(PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum(PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol(PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly(PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability(PubMed:18450749).
    Molekulargewicht
    89 kDa
    Gen-ID
    5007
    UniProt
    P22059
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