OSBP Antikörper
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- Target Alle OSBP Antikörper anzeigen
- OSBP (Oxysterol Binding Protein (OSBP))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OSBP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- oxysterol binding protein
- Isotyp
- IgG
- Top Product
- Discover our top product OSBP Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- OSBP (Oxysterol Binding Protein (OSBP))
- Andere Bezeichnung
- OSBP (OSBP Produkte)
- Synonyme
- CG6708 antikoerper, Dmel\\CG6708 antikoerper, OSBP-Dm antikoerper, osbp antikoerper, OSBP1 antikoerper, 1110018F06Rik antikoerper, AW559088 antikoerper, mKIAA4220 antikoerper, Oxysterol binding protein antikoerper, oxysterol binding protein antikoerper, Osbp antikoerper, OSBP antikoerper
- Hintergrund
- Synonyms:OSBP1 Background:Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate(PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum(PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol(PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly(PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability(PubMed:18450749).
- Molekulargewicht
- 89 kDa
- Gen-ID
- 5007
- UniProt
- P22059
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