OSBPL3 Antikörper

Produktnummer ABIN7117176

Produktdetails anti-OSBPL3 Antikörper

Target: OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OSBPL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: oxysterol binding protein-like 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu OSBPL3

Target: OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))

Andere Bezeichnung: OSBPL3 (OSBPL3 Produkte)

Synonyme: osbpl3 antikoerper, zgc:101089 antikoerper, OSBPL3 antikoerper, ORP-3 antikoerper, ORP3 antikoerper, OSBP3 antikoerper, 1200014M06Rik antikoerper, 6720421I08Rik antikoerper, A530055M08 antikoerper, RGD1564287 antikoerper, oxysterol binding protein like 3 antikoerper, oxysterol binding protein-like 3a antikoerper, oxysterol binding protein-like 3 antikoerper, OSBPL3 antikoerper, osbpl3a antikoerper, osbpl3 antikoerper, Osbpl3 antikoerper

Hintergrund: Synonyms:KIAA0704, ORP3, OSBP3 Background:Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193).

Molekulargewicht: 101 kDa

Gen-ID: 26031

UniProt: Q9H4L5