PHF2 Antikörper
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- Target Alle PHF2 Antikörper anzeigen
- PHF2 (PHD Finger Protein 2 (PHF2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PHF2 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- PHD finger protein 2
- Isotyp
- IgG
- Top Product
- Discover our top product PHF2 Primärantikörper
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anti-PHD Finger Protein 2 (PHF2) (AA 2-100) antibody
PHF2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3E7 unconjugated
anti-PHD Finger Protein 2 (PHF2) (AA 936-985) antibodyPHF2 Reaktivität: Human, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-PHD Finger Protein 2 (PHF2) (Middle Region) antibodyPHF2 Reaktivität: Human, Kaninchen, Rind (Kuh), Pferd, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:200-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- PHF2 (PHD Finger Protein 2 (PHF2))
- Andere Bezeichnung
- PHF2 (PHF2 Produkte)
- Synonyme
- CENP-35 antikoerper, GRC5 antikoerper, JHDM1E antikoerper, im:4200679 antikoerper, phf8 antikoerper, wu:fa14c10 antikoerper, PHD finger protein 2 antikoerper, PHF2 antikoerper, Phf2 antikoerper, phf2 antikoerper
- Hintergrund
- Synonyms:GRC5, JHDM1E, KIAA0662, PHD finger protein 2, PHF2 Background:Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3(H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3(H3K4me3) at rDNA promoters and promotes expression of rDNA.
- Molekulargewicht
- 100 kDa, 150 kDa
- Gen-ID
- 5253
- UniProt
- O75151
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