PLCD4 antikoerper, PLCL3 antikoerper, si:dkeyp-84a8.7 antikoerper, 4921507K24Rik antikoerper, phospholipase C eta 1 antikoerper, phospholipase C delta 4 antikoerper, phospholipase C, delta 4a antikoerper, phospholipase C, delta 4 antikoerper, phospholipase C delta 4 L homeolog antikoerper, PLCH1 antikoerper, PLCD4 antikoerper, plcd4a antikoerper, plcd4 antikoerper, Plcd4 antikoerper, plcd4.L antikoerper
Hintergrund
Synonyms: Background:Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.